One conversational AI interface connecting specialized agents for SOP drafting, audit readiness, CSV, and 21 CFR Part 11 compliance.
Saram ConsultingThoughts and strategies on the intersection of Biotech, Artificial Intelligence, and Regulatory Compliance.
Binary beats scales. Domain experts beat developers. Critiques beat scores. The methodology behind building LLM judges that actually align with what your users care about — drawn from the practitioners and researchers who've done it at scale.
Read Article →In GxP environments, your evaluation dataset is not a benchmark — it is a controlled validation asset that must satisfy ALCOA+, support traceability matrices, and withstand regulatory inspection. Here is how to engineer one.
Read Article →Pydantic AI, Qdrant vector search, SHA-256 hash-chained audit trails, and ALCOA+ compliance scoring — the architecture decisions behind an open-source GxP document drafting system that takes 21 CFR Part 11 seriously.
Read Article →A hands-on playbook for building production-grade semantic search over life sciences quality documents — from basic embedding to hybrid RRF, ColBERT reranking, branch-aware versioning, and dynamic EAV payload indexing. Every tutorial runs 100% local.
Read Article →Most teams pick one evaluation method and wonder why their quality metrics plateau. The real play is composing LLM-as-a-Judge, code evaluators, annotation queues, manual scoring, and API ingestion into a layered system that catches what no single method can.
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